HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chlorotrimethylsilane → HCID 18630201, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chlorotrimethylsilane | HCID 6397 | — |
| Reactant | N-Ethylbenzamide | HCID 11959 | — |
| Product | HCID 18630201 | HCID 18630201 | 68.3% |
Reaction Steps
N-Ethylbenzamide (74.5 g, 500 mmol) and TMSCl (135.8 g, 1.25 mol) were combined according to General Method C and purified by HPLC with 1:4 ethyl acetate/hexanes to afford 75.59 g of the title compound, as a white solid, a 68% yield. m.p. 64.0-66.0° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06248894B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-4ffbef981cb648c39cf9554f024cd749 |
| Source note | uspto-grants-2001_06 |