HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-N,N-diethylbenzamide → n,n-Diethyl-2-chloro-6-[tris(1-methylethyl)silyl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-N,N-diethylbenzamide | HCID 82566 | — |
| Reactant | Triisopropylsilyl chloride | HCID 139400 | — |
| Product | n,n-Diethyl-2-chloro-6-[tris(1-methylethyl)silyl]benzamide | HCID 18630226 | — |
Reaction Steps
The title compound was prepared according to General Method A from the compound of Example e and 1.1 eq triisopropylsilyl chloride. Purification by HPLC using 1:19 ethyl acetate/hexanes gave 5.5 g of the desired product as of a clear oil, a 75% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06248894B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-85adc5c1d0cb4cb08cc748296dcbbb15 |
| Source note | uspto-grants-2001_06 |