HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1068412Generated: October 25, 2026
Hydrochloric Acid → 1-(2-naphthylmethyl)-1H-imidazol-5-ylacetic acid hydrochloride
https://huagongshe.com/reaction/1068412
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-[1-(Naphth-2-ylmethyl)-1H-imidazol-5-yl]acetic acid methyl ester | HCID 53806866 | — |
| Product | 1-(2-naphthylmethyl)-1H-imidazol-5-ylacetic acid hydrochloride | HCID 70206205 | — |
Reaction Steps
2-[1-(Naphth-2-ylmethyl)-1H-imidazol-5-yl]acetic acid methyl ester (0.92 g, 3.28 mmol ) was dissolved in 2.5N hydrochloric acid ( 50 ml) and heated to 55° C. for 3 hr. After this time, the solution was concentrated to dryness in vacuo to give the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06248756B1 |
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| Source dataset | uspto-grants-2001_06 |
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| ORD ID | ord-e6bd748611904974b0a74720850d1113 |
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| Source note | uspto-grants-2001_06 |
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