Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 21193235 | HCID 21193235 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 21193350 | HCID 21193350 | — |
Reaction Steps
A solution of N-tert-butoxycarbonyl-4-hydroxymethyl-4-(3-tolylsulfanyl)piperidine (0.27 g) in dichloromethane (25 mL) at 0° C. was saturated with hydrogen chloride gas. The resultant solution was sealed with a rubber septum and stirred at 0° C. for one h. The product solution was concentrated under vacuum to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06248756B1 |
|---|
| Source dataset | uspto-grants-2001_06 |
|---|
| ORD ID | ord-2c23764cce2045f989598a7a43c879b3 |
|---|
| Source note | uspto-grants-2001_06 |
|---|
