3-Benzoylbenzoic acid → HCID 20666663, compound

HRID 1068848Notes

Reaction equation

[C:1]([C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][CH:17]=1)[C:12]([OH:14])=O)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:18][C@@H:19]([CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[CH2:20][OH:21]>>[C:1]([C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][CH:17]=1)[C:12]([NH:18][C@@H:19]([CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[CH2:20][OH:21])=[O:14])(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 1013863-Benzoylbenzoic acid

HCID 447213phenylalaninol, (S)-

Product 1

HCID 20666663HCID 20666663, compoundYield 79%

Procedure

2 g (8.8 mmol) of 3-benzoylbenzoic acid were reacted with (S)-2-amino-3-phenyl-1-propanol by the method of procedure 3c. 2.5 g (79%) of the product were obtained.

Sources & evidence

ORD record: ord-0fc50f42988842ef95a3b71f1f739598
Source dataset: uspto-grants-2001_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06251917B1

Reaction notes

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