4-Benzoylbenzoic acid → HCID 20666682, compound

HRID 1068853Notes

Reaction equation

[CH:1]1[CH:6]=[CH:5][C:4]([C:7]([C:9]2[CH:14]=[CH:13][C:12]([C:15]([OH:17])=O)=[CH:11][CH:10]=2)=[O:8])=[CH:3][CH:2]=1.[NH2:18][C@@H:19]([CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[CH2:20][OH:21]>>[C:7]([C:9]1[CH:10]=[CH:11][C:12]([C:15]([NH:18][C@@H:19]([CH2:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH2:20][OH:21])=[O:17])=[CH:13][CH:14]=1)(=[O:8])[C:4]1[CH:3]=[CH:2][CH:1]=[CH:6][CH:5]=1

Participants

Reactant 2

HCID 691474-Benzoylbenzoic acid

HCID 447213phenylalaninol, (S)-

Product 1

HCID 20666682HCID 20666682, compoundYield 67%

Procedure

3 g (13 mmol) of benzophenone-4-carboxylic acid were reacted with (S)-2-amino-3-phenyl-1-propanol by the method of procedure 3c. 3.2 g (67%) of the product were obtained.

Sources & evidence

ORD record: ord-3b45d3d75a934d98b7e89d16ae871c23
Source dataset: uspto-grants-2001_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06251917B1

Reaction notes

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