o-Phenylbenzoic acid → HCID 20666654, compound

HRID 1068859Notes

Reaction equation

HRID 1068859 reaction equation
[C:1]1([C:7]2[CH:15]=[CH:14][CH:13]=[CH:12][C:8]=2[C:9]([OH:11])=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH2:16][C@@H:17]([CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[CH2:18][OH:19]>>[C:1]1([C:7]2[CH:15]=[CH:14][CH:13]=[CH:12][C:8]=2[C:9]([NH:16][C@@H:17]([CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH2:18][OH:19])=[O:11])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 70357o-Phenylbenzoic acidHCID 447213phenylalaninol, (S)-

Product 1

HCID 20666654HCID 20666654, compoundYield 64%

Procedure

2 g (10 mmol) of 2-phenylbenzoic acid were reacted with (S)-2-amino-3-phenyl-1-propanol by the method of procedure 3a, affording 2.1 g (64%) of the product.

Sources & evidence

ORD record
ord-c731a65376154c019264a25dd3d92420
Source dataset
uspto-grants-2001_06
Patent number
US06251917B1

Reaction notes

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