phenylalaninol, (S)- → HCID 21190879, compound

HRID 1068865Notes

Reaction equation

HRID 1068865 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=O.[NH2:14][C@@H:15]([CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[CH2:16][OH:17]>>[CH3:1][C:2]1[CH:10]=[CH:9][C:8]([N+:11]([O-:13])=[O:12])=[CH:7][C:3]=1[C:4]([NH:14][CH:15]([CH2:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[CH2:16][OH:17])=[O:6]

Participants

3

Reactant 2

HCID 447213phenylalaninol, (S)-HCID 5196832-Methyl-5-nitrobenzoic acid

Product 1

HCID 21190879HCID 21190879, compoundYield 87%

Procedure

5 g (27.6 mmol) of 2-methyl-5-nitrobenzoic acid were reacted with (S)-2-amino-3-phenyl-1-propanol by the method of procedure 3c. 7.5 g (87%) of the product were obtained.

Sources & evidence

ORD record
ord-d4d669d825664596ad8ce06f426efb69
Source dataset
uspto-grants-2001_06
Patent number
US06251917B1

Reaction notes

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