Benzocaine → HCID 2118845, compound

HRID 1068869Notes

Reaction equation

HRID 1068869 reaction equation
[NH2:1][C:2]1[CH:12]=[CH:11][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:4][CH:3]=1.[CH:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[CH:15][C:14]=1[S:23](Cl)(=[O:25])=[O:24]>>[CH:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[CH:15][C:14]=1[S:23]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:11][CH:12]=1)(=[O:24])=[O:25]

Participants

3

Reactant 2

HCID 2337BenzocaineHCID 71252-Naphthalenesulfonyl chloride

Product 1

HCID 2118845HCID 2118845, compoundYield 64%

Procedure

10 g (60.5 mmol) of ethyl 4-aminobenzoate and 13.7 g (60.5 mmol) of 2-naphthylsulfonyl chloride were reacted by the method of procedure 4b, affording 13.6 g (64%) of the product.

Sources & evidence

ORD record
ord-23fa8d381d3f464faa5b01618a71ef46
Source dataset
uspto-grants-2001_06
Patent number
US06251917B1

Reaction notes

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