HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitrophenylboronic Acid → 5-(3-Nitrophenyl)-2,3-dihydro-7-benzofurancarboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitrophenylboronic Acid | HCID 1677 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Methyl 5-bromo-2,3-dihydrobenzofuran-7-carboxylate | HCID 54179230 | — |
| Catalyst | HCID 178420553 | HCID 178420553 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-(3-Nitrophenyl)-2,3-dihydro-7-benzofurancarboxylic acid methyl ester | HCID 54560655 | — |
Reaction Steps
m.p. 53-57 ° C.; from 5-bromo-2,3-dihydro-7-benzofurancarboxylic acid methyl ester (1.0 g), tetrakis(triphenylphosphino)palladium(0) (103 mg), 2 M sodium carbonate (7.0 mL) and 3-nitrophenylboronic acid (741 mg) in methanol (5 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06251925B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-730182f123984940ad7f59cac7dbba00 |
| Source note | uspto-grants-2001_06 |