HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 5152373, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | 3-Nitrophenylboronic Acid | HCID 1677 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Ethyl 6-Bromopicolinate | HCID 2758810 | — |
| Catalyst | Tetrakis(triphenylphosphine)palladium | HCID 11979704 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 5152373 | HCID 5152373 | — |
Reaction Steps
n.m.r δ values include 1.47 (t, 2.9 H), 4.04 (s, 0.8 H), 4.50 (q, 1.46 H), 7.67 (t, 1 H), 7.97-7.99 (m, 2 H), 8.10-8.16 (m, 1 H), 8.29 (d, 1 H), 8.43-8.48 (m, 1 H), 8.86-8.87 (m, 1 H); from 2-bromo-6-pyridine-carboxylic acid ethyl ester (1.2 g) in toluene (20 mL), tetrakis(triphenylphosphine) palladium(0) (181 mg), 2 M aqueous sodium carbonate (3.3 mL) , and 3-nitrophenylboronic acid (1.0 g) in methanol (5 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06251925B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-e02ad9befa464927873b47e70c1b0fa5 |
| Source note | uspto-grants-2001_06 |