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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1069090Generated: October 29, 2026

(2R)-2-(Phenoxymethyl)oxirane → (R)-3'-[[2-[(2-Hydroxy-3-phenoxypropyl)amino]ethyl]amino]-[1,1'-biphenyl]-3-carboxylic acid methyl ester

https://huagongshe.com/reaction/1069090

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2R)-2-(Phenoxymethyl)oxiraneHCID 1534344—
Reactant3'-(2-Amino-ethylamino)-biphenyl-3-carboxylic acid methyl esterHCID 21191167—
Product(R)-3'-[[2-[(2-Hydroxy-3-phenoxypropyl)amino]ethyl]amino]-[1,1'-biphenyl]-3-carboxylic acid methyl esterHCID 54573255—

Reaction Steps

Electrospray MS (positive ion): (M+H) 421.1; from methyl-3′-[(2-aminoethyl)amino]-[1,1′-biphenyl]-3-carboxylate (117 mg) and (R)-(-)-3-(phenyloxy)-1,2-epoxypropane (54 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06251925B1
Source datasetuspto-grants-2001_06
ORD IDord-b318394577c74edeb0b3136747dd1ee6
Source noteuspto-grants-2001_06