Sodium Acetate → HCID 2885488, compound

HRID 1069129Notes

Reaction equation

HRID 1069129 reaction equation
[C:1]1([CH2:11][O:12][C:13]2[CH:20]=[CH:19][C:16]([CH:17]=O)=[CH:15][CH:14]=2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.C([O-])(=O)C.[Na+].[S:26]1[CH2:32][C:30](=[O:31])[NH:29][C:27]1=[S:28]>C(O)(=O)C>[C:1]1([CH2:11][O:12][C:13]2[CH:20]=[CH:19][C:16]([CH:17]=[C:32]3[S:26][C:27](=[S:28])[NH:29][C:30]3=[O:31])=[CH:15][CH:14]=2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 881941HCID 881941, compoundHCID 1201546Rhodanine

Product 1

HCID 2885488HCID 2885488, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Under a nitrogen atmosphere in a round bottom flask 4-[(naphth-1-yl)methoxy]benzaldehyde (5.25 g, 20 mmol) was dissolved in 100 ml of acetic acid. To this solution was added sodium acetate (5.74 g, 70 mmol) and rhodanine (2.66 g, 20 mmol). The reaction mixture was raised to the reflux temperature and maintained at this temperature. The progress of the reaction was monitored by thin layer chomratography.

Workup

  1. temperatureThe reaction mixture was raised to the reflux temperature
  2. temperaturemaintained at this temperature

Sources & evidence

ORD record
ord-b5bb25d61a364fe3bb4fa90dcbf4ea58
Source dataset
uspto-grants-2001_06
Patent number
US06251928B1

Reaction notes

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