Sodium Acetate → HCID 86752510, compound

HRID 1069130Notes

Reaction equation

HRID 1069130 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][O:12][C:13]1[CH:20]=[CH:19][C:16]([CH:17]=O)=[CH:15][CH:14]=1.C([O-])(=O)C.[Na+].[S:26]1[CH2:32][C:30](=[O:31])[NH:29][C:27]1=[S:28]>C(O)(=O)C>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[CH2:11][O:12][C:13]1[CH:20]=[CH:19][C:16]([CH:17]=[C:32]2[S:26][C:27](=[S:28])[NH:29][C:30]2=[O:31])=[CH:15][CH:14]=1

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 6728764-(2-naphthylmethoxy)benzaldehydeHCID 1201546Rhodanine

Product 1

HCID 86752510HCID 86752510, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Under a nitrogen atmosphere in a round bottom flask 4-[(naphth-2-yl)methoxy]benzaldehyde (5.24 g, 20 mmol) was dissolved in 100 ml of acetic acid. To this solution was added sodium acetate (5.74 g, 70 mmol) and rhodanine (2.66 g, 20 mmol). The reaction mixture was raised to the reflux temperature and maintained at this temperature. The progress of the reaction was monitored by thin layer chomratography.

Workup

  1. temperatureThe reaction mixture was raised to the reflux temperature
  2. temperaturemaintained at this temperature

Sources & evidence

ORD record
ord-8d623421c1a5402e84dbccfa039c8eca
Source dataset
uspto-grants-2001_06
Patent number
US06251928B1

Reaction notes

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