HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → 5-[[4-[(4-Decanoyl-3-hydroxy-2-propylphenoxy)methyl]phenyl]methylene]-2-thioxo-4-thiazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | Rhodanine | HCID 1201546 | — |
| Reactant | 4-[(4-Decanoyl-3-hydroxy-2-propylphenoxy)methyl]benzaldehyde | HCID 21191247 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5-[[4-[(4-Decanoyl-3-hydroxy-2-propylphenoxy)methyl]phenyl]methylene]-2-thioxo-4-thiazolidinone | HCID 86752517 | 84% |
Reaction Steps
The 4-[(4-decanoyl-3-hydroxy-2-propylphenoxy)methyl]benzaldehyde thus obtained was coupled with the rhodanine by reacting equimolar amounts of the benzaldehyde and the rhodanine in the presence of sodium acetate and acetic acid as previously described to yield 1.6 g (84%) of the title product. mp 187.5-188° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06251928B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-25335eb8aa7c450a80b51f4bd6bbd756 |
| Source note | uspto-grants-2001_06 |