Acetonitrile → HCID 70071560, compound

Participants

Reaction Steps

The compound of Example 13 (0.49 g, 1.3 mmol) was dissolved in ACOH and hydrogenated with 4% Pd/C (53% wet, 0.050 g) in a Parr Shaker (60 psi, 60C). The catalyst was filtered off and the filtrate concentrated in vacuo to give a white solid. The solid was slurried with acetonitrile and the resulting white solid was collected by vacuum filtration (0.423 g). Analysis Calculated for C20H23N3O3.1.6 AcOH: C, 61.99; H, 6.59; N, 9.35. Found: C, 61.81; H, 6.50; N, 9.42. M+=353.

Provenance & Evidence