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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1069183Generated: October 29, 2026

3,3-Dimethylbutanal → [1-(3,3-Dimethyl-butyl)-piperidin-4-yl]-(4-isopropyl-phenyl)-(3-methyl-but-2-enyl)-amine

https://huagongshe.com/reaction/1069183

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,3-DimethylbutanalHCID 76335—
Reactant(4-Benzyloxy-phenyl)-(3-methyl-but-2-enyl)-piperidin-4-yl-amineHCID 10641624—
Reactant(4-Isopropyl-pbenyl)-(3-methyl-but-2-enyl)-piperidin-4-yl-amineHCID 21191011—
Product[1-(3,3-Dimethyl-butyl)-piperidin-4-yl]-(4-isopropyl-phenyl)-(3-methyl-but-2-enyl)-amineHCID 21191049—

Reaction Steps

The preparation of Example 26: [1-(3,3-Dimethyl-butyl)-piperidin-4-yl]-(4-isopropyl-phenyl)-(3-methyl-but-2-enyl)-amine was prepared in accordance with the methods of Step 4 in Example 1, except that (4-Isopropyl-phenyl)-(3-methyl-but-2-enyl)-piperidin4-yl-amine (26c) was used instead of (4-Benzyloxy-phenyl-(3-methyl-but-2-enyl)-piperidin-4-yl-amine (Ic) and 3,3-dimethylbutyraldehyde was used instead of isovaleraldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06251919B1
Source datasetuspto-grants-2001_06
ORD IDord-73d628738e534ef6b0ed200fea14ff71
Source noteuspto-grants-2001_06