HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10852391, compound → HCID 10732550, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10852391 | HCID 10852391 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 10732550 | HCID 10732550 | 95.6% |
Reaction Steps
One gram of Raney nickel was added to 790 mg (2.4 mmol) of 5-methoxy-1-(phenylmethyl)-1H-indole-3-acetic acid hydrazide in 120 mL of EtOH and the mixture heated at reflux for 2 hours. After filtering off the catalyst, the filtrate was concentrated at reduced pressure and the residue triturated with ether to give 675 mg (89% yield) of 5-methoxy-1-(phenylmethyl)-1H-indole-3-acetamide, mp, 156-158° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06252084B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-a14f1e119cf24c02bc280998439b2042 |
| Source note | uspto-grants-2001_06 |