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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1069552Generated: October 29, 2026

HCID 10852391, compound → HCID 10732550, compound

https://huagongshe.com/reaction/1069552

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 10852391HCID 10852391—
CatalystNickelHCID 935—
SolventEthanolHCID 702—
ProductHCID 10732550HCID 1073255095.6%

Reaction Steps

One gram of Raney nickel was added to 790 mg (2.4 mmol) of 5-methoxy-1-(phenylmethyl)-1H-indole-3-acetic acid hydrazide in 120 mL of EtOH and the mixture heated at reflux for 2 hours. After filtering off the catalyst, the filtrate was concentrated at reduced pressure and the residue triturated with ether to give 675 mg (89% yield) of 5-methoxy-1-(phenylmethyl)-1H-indole-3-acetamide, mp, 156-158° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06252084B1
Source datasetuspto-grants-2001_06
ORD IDord-a14f1e119cf24c02bc280998439b2042
Source noteuspto-grants-2001_06