HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine → Diethyl Ether
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | HCID 10687376 | HCID 10687376 | — |
| Reactant | HCID 10806873 | HCID 10806873 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Diethyl Ether | HCID 3283 | 96% |
| Product | 3-Indoleacetic acid hydrazide | HCID 21589 | — |
Reaction Steps
5-Methoxy-2-methyl-1-(phenylmethyl)-1H-indole-3-acetic acid hydrazide. A solution of 1.0 g (2.96 mmol) of 5-methoxy-2-methyl-1-(phenylmethyl)-1H-indole-3-acetic acid ethyl ester and 5 mL of hydrazine in 50 mL of MeOH was reacted as described in Example 3, Part C, to give by trituration with ether 920 mg (96% yield) of 5-methoxy-2-methyl-1-phenylmethyl)-1H-indole-3-acetic acid hydrazide, mp, 161-162° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06252084B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-cefd4666070946ac8dfad251bf1f0eb1 |
| Source note | uspto-grants-2001_06 |