HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylsilane → HCID 10522282, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylsilane | HCID 12052 | — |
| Reactant | HCID 10643060 | HCID 10643060 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 10522282 | HCID 10522282 | — |
Reaction Steps
By the method in Example 75, Part F, 280 mg (0.75 mmol) of 1-[(3-chlorophenyl)methyl]-2-ethyl-4-methoxy-alpha-hydroxy-1H-indole-3-acetamide was reduced with 0.12 mL (0.75 mmol) of triethylsilane in 2 mL of trifluoroacetic acid to give by chromatography on silica gel (eluted ethyl acetate) 125 mg (48% yield) of 1-[(3-chlorophenyl)methyl]-2-ethyl-4-methoxy-1H-indole-3-acetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06252084B1 |
| Source dataset | uspto-grants-2001_06 |
| ORD ID | ord-9ea678b9e5164aa9a67d2d4896700846 |
| Source note | uspto-grants-2001_06 |