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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1069735Generated: October 29, 2026

N-(tert-Butoxycarbonyl)-D-prolinol → N-(tert-Butoxycarbonyl)-D-prolinal

https://huagongshe.com/reaction/1069735

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(tert-Butoxycarbonyl)-D-prolinolHCID 688279—
ReactantCbz-L-ProlinolHCID 11096562—
ProductN-(tert-Butoxycarbonyl)-D-prolinalHCID 7009153—

Reaction Steps

(R)-N-Boc-2-Formyl-pyrrolidine was prepared by Swern oxidation of (R)-N-Boc prolinol (Fluka) using the procedure for the oxidation of CBZ-prolinol described by of M. G. B. Drew et al. supra.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06252086B1
Source datasetuspto-grants-2001_06
ORD IDord-88c4b57439384b709f19a5bf8b87f3b5
Source noteuspto-grants-2001_06