1-Hexene → 2-Octanone

Participants

Reaction Steps

Under the same reaction procedure and conditions as in Example 2 (tristriphenylphosphine rhodium (I) chloride 10 mol %, 150° C., 48 hours, toluene 100 mg), benzyl acetone 32 mg (0.22 mmol) and 1-hexene 182 mg (2.16 mmol) were reacted in the presence of various amounts of 2-amino-3-pycoline. A measurement was made of the yields of 2-octanone, and the results are given in Table 4, below. When 2-amino-3-pycoline was absent, 2-octanone was not obtained at all and benzyl acetone was recovered in its entirety.

Provenance & Evidence