Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → N-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyloxy]phthalimide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | N-Hydroxyphthalimide | HCID 10665 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 4-(4-Chloromethylphenoxy)methyl-5-methyl-2-phenyloxazole | HCID 10946940 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | N-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyloxy]phthalimide | HCID 22344648 | 93% |
반응 단계
A mixture of 4-(4-chloromethylphenoxymethyl)-5-methyl-2-phenyloxazole (5.00 g), N-hydroxyphthalimide (2.59 g), potassium carbonate (4.40 g) and N,N-dimethylformamide (50 ml) was stirred at room temperature for 20 hours, and water (500 ml) was added. The resultant crystals were filtered, and washed with water to obtain N-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyloxy]phthalimide (6.49 g, yield 93%) as colorless crystals. m.p. 155-156° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06251926B1 |
| 출처 데이터셋 | uspto-grants-2001_06 |
| ORD ID | ord-df05fba10dfe440a8b38d920577ee9e3 |
| 출처 메모 | uspto-grants-2001_06 |