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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1070225Generated: November 2, 2026

Diethylamine → N,N-Diethyl-2,5-bis(trifluoromethyl)benzamide

https://huagongshe.com/reaction/1070225

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethylamineHCID 8021—
Reactant2,5-Bis(trifluoromethyl)benzoyl chlorideHCID 2737812—
ProductN,N-Diethyl-2,5-bis(trifluoromethyl)benzamideHCID 15832108—

Reaction Steps

N,N-Diethyl-2,5-bis(trifluoromethyl)benzamide was prepared from 2,5-bis(trifluoromethyl)benzoyl chloride and diethylamine according to General Method E1. The desired intermediate was isolated in quantitative yield (11.3 g) without additional purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06252078B1
Source datasetuspto-grants-2001_06
ORD IDord-75682841eb294881982d65158ed2af01
Source noteuspto-grants-2001_06