2-Nitro-5-(propan-2-yloxy)benzoic acid → 2-Amino-5-(propan-2-yloxy)benzoic acid

Participants

Reaction Steps

To a solution of 5-isopropoxy-2-nitro-benzoic acid (946 mg, 4.2 mmol) in THF (15 mL) was added 5% Pd/C (95 mg) under a nitrogen atmosphere. A balloon filled with H2 was set up. The mixture was stirred for 3.5 h and filtered. The filtrate was dried to yield 816 mg of 5-isopropoxy-2-amino-benzoic acid.

Provenance & Evidence