HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dihexylamine → 4-(N,N-di-n-hexylamino)-3-ethoxy-1,1-dioxo-1,2,5-thiadiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dihexylamine | HCID 8920 | — |
| Reactant | 3,4-Diethoxy-1,2,5-thiadiazole-1,1-dioxide | HCID 11217995 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(N,N-di-n-hexylamino)-3-ethoxy-1,1-dioxo-1,2,5-thiadiazole | HCID 22138787 | 72.4% |
Reaction Steps
Dihexylamine (90 mg, 0.48 mmol) was added to a solution of 3,4-diethyloxy-1,1-dioxo-1,2,5-thiadiazole (100 mg, 0.48 mmol) in ethanol (5 mL) and the reaction stirred overnight at room temperature. The solvent was removed under reduced pressure and the residue absorbed onto silica gel, and purified by flash column chromatography (silica, hexane:EtOAc 3:1) to yield 4-(N,N-di-n-hexylamino)-3-ethoxy-1,1-dioxo-1,2,5-thiadiazole (120 mg, 72%). MS (EI, m/e 345).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06903088B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-4b9312f0618d4a37908a288d1453df9a |
| Source note | uspto-grants-2005_06 |