HRID1070445

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCCCCN(CCCCCC)C1=NS(=O)(=O)N=C1N[C@@H](Cc1ccc(O)cc1)C(=O)OC(C)(C)C

HCID178444783

未命名化合物

PRODUCTS

生成物

结构：CCCCCCN(CCCCCC)C1=NS(=O)(=O)N=C1N[C@@H](Cc1ccc(O)cc1)C(=O)O

HCID178444782

未命名化合物

收率 98.6%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID284

Formic acid

CH2O2

PROCEDURE

实验过程

N-(4-(N,N-Di-n-hexylamino)-1,1-dioxo-1,2,5-thiadiazol-3-yl)-L-tyrosine tert-butyl ester (100 mg, 0.19 mmol) was dissolved in formic acid and the mixture stirred at room temperature for 36 hrs. Excess formic acid was removed under reduced pressure to yield N-(4-(N,N-Di-n-hexylamino)-1,1-dioxo-1,2,5-thiadiazol-3-yl)-L-tyrosine as a white solid (90 mg, 98%). Anal. Calc'd for C23H36N4O5S: C, 57.48; H, 7.55; N, 11.66. Found: C,57.04; H, 7.23; N,11.38.

WORKUP

后处理

customExcess formic acid was removed under reduced pressure