HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-BOC-ethylenediamine → HCID 22396192, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-BOC-ethylenediamine | HCID 187201 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | 3,4-dichlorobenzyl-4-piperidone | HCID 10848776 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22396192 | HCID 22396192 | — |
Reaction Steps
A solution of the product from step (i) (1.61 g), N-(tert-butoxycarbonyl)-ethylenediamine (1 g) and sodium triacetoxyborohydride (2.12 g) in dichloromethane (20 ml) was stirred at room temperature for 3 h. The mixture was partitioned between water and ethyl acetate, the organic layer dried and evaporated under reduced pressure. Yield 1.28 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06903085B1 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-580f275b589746b4bc43ed6206780079 |
| Source note | uspto-grants-2005_06 |