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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1070521Generated: October 29, 2026

Sodium cyanoborohydride → (R)-1-[1-(4-Bromophenyl)ethyl]-4-piperidinamine

https://huagongshe.com/reaction/1070521

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium cyanoborohydrideHCID 5003444—
Reactant(R)-1-(1-(4-Bromophenyl)ethyl)piperidin-4-oneHCID 28296279—
Product(R)-1-[1-(4-Bromophenyl)ethyl]-4-piperidinamineHCID 68884300106.5%

Reaction Steps

Prepared following the general method of Example 370 step (i) (R)-1-[1-(4-bromophenyl)ethyl]-4-piperidinone (420 mg) ammonium acetate (0.80 g) and sodium cyanoborohydride (120 mg) to give the subtitle compound (449 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06903085B1
Source datasetuspto-grants-2005_06
ORD IDord-818c63f1ad3d4af6acb404fbabdc4b52
Source noteuspto-grants-2005_06