tert-Butyl Formate → HCID 22397346, compound

HRID 1070560Notes

Reaction equation

HRID 1070560 reaction equation
[C:1]([O:5][C:6]([N:8]([CH:14]1[CH2:18][CH2:17][CH2:16][CH2:15]1)[CH2:9][CH2:10][C:11]([O-])=[O:12])=[O:7])([CH3:4])([CH3:3])[CH3:2].C(OC(C)(C)C)=O>C(OCC)(=O)C.CCCCCCC>[C:1]([O:5][C:6]([N:8]([CH:14]1[CH2:15][CH2:16][CH2:17][CH2:18]1)[CH2:9][CH2:10][CH2:11][OH:12])=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 61207tert-Butyl FormateHCID 22397336HCID 22397336, compound

Product 1

HCID 22397346HCID 22397346, compound

Reagents, catalysts & solvents 1

HCID 21899848Ethylacetate heptaneSolvent

Procedure

This compound was prepared from N-tert-butoxycarbonyl-3-cyclopentylamino-propanoate (3a, 2.28 g, 8.0 mmol) using the procedure described in Example 2b. Yield: 1.34 g (69%). ESI-MS: 244.2 (M+H)+, 266.3 (M+Na)+, 188.2 (M+H—C4H8)+, 144.2 (M+H-Boc)+. Rf (silica gel; ethyl acetate/heptane, 1:4, v/v): 0.30.

Sources & evidence

ORD record
ord-7bdcfdd8262746f68223d4e0088fdcf0
Source dataset
uspto-grants-2005_06
Patent number
US06903107B1

Reaction notes

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