HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 69491289, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(N-Boc-amino)piperidine | HCID 723833 | — |
| Reactant | Bis(tetrabutylammonium) sulphate | HCID 11433187 | — |
| Reactant | 3-(2-bromoethyl)Benzofuran | HCID 15075480 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 69491289 | HCID 69491289 | — |
Reaction Steps
10 mmol of 2-(benzofuran-3-yl)-1-bromoethane, 9.62 mmol of tert-butyl 4-piperidyl-carbamate, 2.65 g of potassium carbonate and 0.65 g of tetrabutylammonium sulphate are added to 10 ml of toluene. After refluxing for 12 hours, the mixture is taken up in water. The organic phase is then washed with water, dried and then filtered. Evaporation under reduced pressure allows the expected product to be isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06903103B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-b02994517173479192fe4031258aafe2 |
| Source note | uspto-grants-2005_06 |