HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → HCID 69687009, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3-(3-Pyridinyl)-2-propenoic acid | HCID 101984 | — |
| Reactant | tert-Butyl 4-(2-aminoethyl)piperazine-1-carboxylate | HCID 1514400 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 69687009 | HCID 69687009 | — |
Reaction Steps
Batch size: 36.1 g (242 mmol) 3-(3-pyridyl)-acrylic acid, 23.1 ml (264 mmol) oxalyl chloride, 50 g (15.4 mmol) 2-[4-(tert-but-oxycarbonyl)-piperazin-1-yl]-ethylamine and 30.4 ml (220 mmol) TEA in 400 ml absolute dichloromethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06903118B1 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-09179638e3b04a42bd87807c42e69ce8 |
| Source note | uspto-grants-2005_06 |