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HRID 1070806作成日：2026年10月25日

trans-2-Phenylcyclopropyl isocyanate → N-[4-(4-amino-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)butyl]-N'-[(1R*,2S*)-2-phenylcyclopropyl]urea

https://huagongshe.com/reaction/1070806

反応式

関与物質

役割名称HCID仕込み量
反応物trans-2-Phenylcyclopropyl isocyanateHCID 255285—
反応物1-(4-aminobutyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-4-amineHCID 21973808—
生成物N-[4-(4-amino-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)butyl]-N'-[(1R*,2S*)-2-phenylcyclopropyl]ureaHCID 20575812—

反応手順

Using the method of Examples 16-26, trans-2-phenylcyclopropyl isocyanate was reacted with 1-(4-aminobutyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 393.2425.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06903113B2
出典データセットuspto-grants-2005_06
ORD IDord-3c48bb7c0a1a4b7392f17e08e8a95e10
出典メモuspto-grants-2005_06