2-Furoyl isothiocyanate → HCID 22397380, compound

HRID 1070808Notes

Reaction equation

HRID 1070808 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([N:8]=[C:9]=[S:10])=[O:7].[CH2:11]([O:13][CH2:14][C:15]1[NH:16][C:17]2[CH:22]=[C:21]([CH3:23])[N:20]=[C:19]([NH2:24])[C:18]=2[N:25]=1)[CH3:12]>>[NH2:24][C:19]1[C:18]2[N:25]=[C:15]([CH2:14][O:13][CH2:11][CH3:12])[N:16]([CH2:4][CH2:3][CH2:2][CH2:6][NH:8][C:9]([NH:8][C:6]([C:2]3[O:1][CH:5]=[CH:4][CH:3]=3)=[O:7])=[S:10])[C:17]=2[CH:22]=[C:21]([CH3:23])[N:20]=1

Participants

3

Reactant 2

HCID 27592432-Furoyl isothiocyanateHCID 86759760HCID 86759760, compound

Product 1

HCID 22397380HCID 22397380, compound

Procedure

Using the method of Examples 36-45, 2-furoylisothiocyanate was reacted with 1-aminobutyl)-2-ethoxymethyl-6-methyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 431.887.

Sources & evidence

ORD record
ord-434845ea0fbe48b09d1b06ed2975afba
Source dataset
uspto-grants-2005_06
Patent number
US06903113B2

Reaction notes

Loading…