4-Morpholinecarbonyl chloride → HCID 10287377, compound

HRID 1070817Notes

Reaction equation

HRID 1070817 reaction equation
[N:1]1([C:7](Cl)=[O:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[NH2:10][CH2:11][CH2:12][CH2:13][N:14]1[C:22]2[C:21]([CH3:23])=[C:20]([CH3:24])[N:19]=[C:18]([NH2:25])[C:17]=2[N:16]=[C:15]1[CH2:26][O:27][CH2:28][CH3:29]>>[NH2:25][C:18]1[C:17]2[N:16]=[C:15]([CH2:26][O:27][CH2:28][CH3:29])[N:14]([CH2:13][CH2:12][CH2:11][NH:10][C:7]([N:1]3[CH2:6][CH2:5][O:4][CH2:3][CH2:2]3)=[O:8])[C:22]=2[C:21]([CH3:23])=[C:20]([CH3:24])[N:19]=1

Participants

3

Reactant 2

HCID 848104-Morpholinecarbonyl chlorideHCID 219738361-(3-aminopropyl)-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-4-amine

Product 1

HCID 10287377HCID 10287377, compound

Procedure

Using the method of Examples 94-105, 4-morpholinecarbonyl chloride was reacted with 1-(3-aminopropyl)-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 391.2465.

Sources & evidence

ORD record
ord-9072eefbb0c54108ada55975a008ac7e
Source dataset
uspto-grants-2005_06
Patent number
US06903113B2

Reaction notes

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