Ethanol → Carbamic acid, [(1S)-2-(3,5-difluorophenyl)-1-(2R)-oxiranylethyl]-,1,1-dimethylethyl ester

HRID 107082Notes

Reaction equation

HRID 107082 reaction equation
[CH3:25][CH2:26][OH:27].[Cl:1][CH2:2][CH:3]([CH:4]([CH2:5][c:6]1[cH:7][c:8]([F:13])[cH:9][c:10]([F:12])[cH:11]1)[NH:14][C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[OH:22].[K+:24].[OH-:23]>>[CH2:2]1[CH:3]([CH:4]([CH2:5][c:6]2[cH:7][c:8]([F:13])[cH:9][c:10]([F:12])[cH:11]2)[NH:14][C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[O:22]1

Participants

5

Reactant 4

HCID 702EthanolHCID 813Potassium CationHCID 961HydroxideHCID 20755995tert-butyl N-[3-chloro-1-[(3,5-difluorophenyl)methyl]-2-hydroxy-propyl]carbamate

Product 1

HCID 20726936Carbamic acid, [(1S)-2-(3,5-difluorophenyl)-1-(2R)-oxiranylethyl]-,1,1-dimethylethyl ester

Sources & evidence

ORD record
ord-3fdd801c476344ca80da09ae85dea4fe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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