trans-2-Phenylcyclopropyl isocyanate → N-{4-[4-amino-2-(ethoxymethyl)-7-methyl-1H-imidazo[4,5-c]pyridin-1-yl]butyl}-N'-[(1R,2S)-2-phenylcyclopropyl]urea

Participants

Role	Name	HCID	Charge
Reactant	trans-2-Phenylcyclopropyl isocyanate	HCID 255285	—
Reactant	1-(4-aminobutyl)-2-(ethoxymethyl)-7-methyl-1H-imidazo[4,5-c]pyridin-4-amine	HCID 21946026	—
Product	N-{4-[4-amino-2-(ethoxymethyl)-7-methyl-1H-imidazo[4,5-c]pyridin-1-yl]butyl}-N'-[(1R,2S)-2-phenylcyclopropyl]urea	HCID 21307072	—

Reaction Steps

Using the method of Examples 147-164, trans-2-phenylcyclopropyl isocyanate was reacted with 1-(4-aminobutyl)-2-(ethoxymethyl)-7-methyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 437.2668.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06903113B2
Source dataset	uspto-grants-2005_06
ORD ID	ord-8549cadd36ac4415bb727bf1b331f982
Source note	uspto-grants-2005_06