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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1070854생성일: 2026년 10월 25일

2-Chloropyridine → 6-[[1-(4-Methylphenyl)-2-(2-pyridinyl)mercapto-1H-benzimidazol-6-yl]oxy]Hexanoic Acid Methyl Ester

https://huagongshe.com/reaction/1070854

반응식

참여 물질

역할이름HCID투입량
반응물2-ChloropyridineHCID 7977—
반응물HCID 178500330HCID 178500330—
생성물6-[[1-(4-Methylphenyl)-2-(2-pyridinyl)mercapto-1H-benzimidazol-6-yl]oxy]Hexanoic Acid Methyl EsterHCID 69688845—

반응 단계

200 mg of 6-[[1-(4-methylphenyl)-2-mercapto-1H-benzimidazol-6-yl]oxy]hexanoic acid methyl ester was heated to 150° C. with 80 μl of 2-chloropyridine for 14 hours. After another 200 μl of 2-chloropyridine was added, it was heated for 3 hours to 170° C. After cooling, it was purified by column chromatography on silica gel. 40 mg was obtained.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06903126B2
출처 데이터셋uspto-grants-2005_06
ORD IDord-c5993bdccf064c6c90999c17c564a970
출처 메모uspto-grants-2005_06