HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Fluoroimidazo[1,2-a]pyridine-2-carboxylic acid → 5-Methylimidazo[1,2-a]pyridine-2-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Fluoroimidazo[1,2-a]pyridine-2-carboxylic acid | HCID 22397508 | — |
| Reactant | 5-Methyl-1,8a-dihydro-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester | HCID 69432298 | — |
| Product | 5-Methylimidazo[1,2-a]pyridine-2-carboxylic acid | HCID 2062169 | — |
| Product | 6-Methylimidazo[1,2-a]pyridine-2-carboxylic acid | HCID 2759863 | — |
| Product | Ethyl 6-methylimidazo(1,2-a)pyridine-2-carboxylate | HCID 12558372 | — |
Reaction Steps
5-Methyl-imidazo[1,2-a]pyridine-2-carboxylic acid was prepared in a similar manner to 6-fluoro-imidazo[1,2-a]pyridine-2-carboxylic acid (see Example 25) using the commercially available 5-methyl-1,8a-dihydro-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester. 6-Methyl-imidazo[1,2-a]pyridine-2-carboxylic acid and 6-methyl-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester were prepared in a similar manner to 6-fluoro-imidazo[1,2-a]pyridine-2-carboxylic acid and its ester above.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06903115B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-ab89e9ca34bb40fe903cf215b5456f93 |
| Source note | uspto-grants-2005_06 |