Benzene, (2-bromoethoxy)- → HCID 22396720, compound

Participants

Reaction Steps

To a solution of tert-butyl 10-(2,4-dichlorophenyl)-1,4,5,5a,6,10b-hexahydroazepino[4,5-b]indole-3(2H)-carboxylate (54 mg) in DMF (1.2 ml) was added KH (10 mg) and 2-bromoethyl phenyl ether (30 mg). The reaction mixture was stirred 24 h, poured into satd NaHCO3, extracted with CH2Cl2, dried over MgSO4, filtered and concentrated. Purification via flash chromatography provided the title compound: 1H NMR (CDCl3) δ 1.63, 2.30-2.50, 2.92, 3.14, 3.42, 3.75, 4.26, 4.53, 6.84, 6.96, 7.20-7.51.

Provenance & Evidence