HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2,2-dimethylpent-4-ynoate → 3-[3-(1-tert-Butoxycarbonylamino-3-methyl-butyl)-isoxazol-5-yl]-2,2-dimethyl-propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2,2-dimethylpent-4-ynoate | HCID 13134461 | — |
| Reactant | [1-(Hydroxyimino-methyl)-3-methyl-butyl]-carbamic acid tert-butyl ester | HCID 73685451 | — |
| Product | 3-[3-(1-tert-Butoxycarbonylamino-3-methyl-butyl)-isoxazol-5-yl]-2,2-dimethyl-propionic acid methyl ester | HCID 20610298 | — |
Reaction Steps
Prepared from [1-(hydroxyimino-methyl)-3-methyl-butyl]-carbamic acid tert-butyl ester (7I) and 2,2-dimethyl-pent-4-ynoic acid methyl ester according to the procedure outlined in example 6A. MS (Cl) m/z: 313.2 (M-tBu), 269.3 (M−99)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06903128B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-3898f46c6f1e48f5bc8643d33645ae28 |
| Source note | uspto-grants-2005_06 |