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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1071320Generated: November 3, 2026

3-(4-Chlorobenzoyl)propionic acid → 1-(4-Chlorophenyl)-4-((S)-hexahydropyrrolo[1,2-a]pyrazin-2-yl)butane-1,4-dione

https://huagongshe.com/reaction/1071320

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(4-Chlorobenzoyl)propionic acidHCID 77604—
Reactant1-(3,4-Dimethoxyphenyl)-4-((S)-hexahydropyrrolo[1,2-a]pyrazin-2-yl)butane-1,4-dioneHCID 24886334—
Product1-(4-Chlorophenyl)-4-((S)-hexahydropyrrolo[1,2-a]pyrazin-2-yl)butane-1,4-dioneHCID 24886335—

Reaction Steps

279 mg of the title compound were prepared as described for 1-(3,4-dimethoxyphenyl)-4-((S)-hexahydropyrrolo[1,2-a]pyrazin-2-yl)butane-1,4-dione, using 3-(4-chlorobenzoyl)propionic acid instead of 3-(3,4-dimethoxybenzoyl)propionic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06906060B2
Source datasetuspto-grants-2005_06
ORD IDord-313f7c30a24e43d09c62ce55fe045d36
Source noteuspto-grants-2005_06