4-Fluorobenzophenone → HCID 20799062, compound

HRID 1071328Notes

Reaction equation

HRID 1071328 reaction equation
F[C:2]1[CH:3]=[C:4]([C:19]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)=[O:20])[CH:5]=[C:6](F)[C:7]=1[N:8]1[CH2:13][CH2:12][N:11]2[CH2:14][CH2:15][CH2:16][CH2:17][C@@H:10]2[CH2:9]1.FC1C=CC(C(C2C=CC=CC=2)=O)=CC=1>>[CH2:9]1[N:8]([C:7]2[CH:2]=[CH:3][C:4]([C:19]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[O:20])=[CH:5][CH:6]=2)[CH2:13][CH2:12][N:11]2[CH2:14][CH2:15][CH2:16][CH2:17][C@H:10]12

Participants

3

Reactant 2

HCID 676634-FluorobenzophenoneHCID 24886802HCID 24886802, compound

Product 1

HCID 20799062HCID 20799062, compound

Procedure

180 mg of the title compound were prepared as described for [3,5-difluoro-4-((R)-octahydropyrido[1,2-a]pyrazin-2-yl)phenyl]-[phenyl]methanone, using 4-fluorobenzophenone instead of 3,4,5-trifluorobenzophenone.

Sources & evidence

ORD record
ord-0592fb3ee988419dabfa3aef2dc08239
Source dataset
uspto-grants-2005_06
Patent number
US06906060B2

Reaction notes

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