HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromo-1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalene → (Z)-5-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-2-(trimethylsilyl)vinyl]thiophene-2-ylmethyl alcohol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromo-1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalene | HCID 226685 | — |
| Reactant | 5-[(Trimethylsilyl)ethynyl]thiophen-2-ylmethyl Tert-butyldiphenylsilyl Ether | HCID 22393094 | — |
| Product | (Z)-5-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-2-(trimethylsilyl)vinyl]thiophene-2-ylmethyl alcohol | HCID 69723741 | — |
Reaction Steps
Following General Procedure A, 5-[(trimethylsilyl)ethynyl]thiophen-2-ylmethyl tert-butyldiphenylsilyl ether (Compound 13, 0.75 g, 1.8 mmol) and 2-bromo-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene (0.46 g, 1.62 mmol) were coupled to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06906057B1 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-1cd422b5759c4ab19a5d74a0fe990a71 |
| Source note | uspto-grants-2005_06 |