2,5-Dioxo-1,3-diazolidin-4-ylacetic acid → HCID 9887473, compound

Participants

Reaction Steps

Commercially available (+/−)hydantoin-5-acetic acid (100 mg, 0.63 mmol) and 4-[(2-methyl-4-quinolinyl)methoxy]-aniline bis-HCl salt (213 mg, 0.63 mmol) were warmed in 1 mL dry DMSO and coupled using GENERAL COUPLING METHOD A. Purified on silica gel using 5% MeOH in EtOAc to give 116 mg (46%) of a white waxy solid. MS found:(M+H)+=406.

Provenance & Evidence