HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 10224744, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Hydantoin | HCID 10006 | — |
| Reactant | HCID 13126067 | HCID 13126067 | — |
| Reactant | HCID 22392771 | HCID 22392771 | — |
| Product | HCID 10224744 | HCID 10224744 | 30.8% |
Reaction Steps
5-(aminomethyl)-5-methylhydantoin (109a) (30 mg, 0.17 mmol) was coupled with {4-[(2-methyl-4-quinolinyl)-methoxy]phenyl}acetic acid (46 mg, 0.15 mmol) using general coupling method B to give 20 mg (24%) of the product hydantoin as a TFA salt. MS found: (M+H)+=433.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06906053B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-ad995ef671b945f6b683fcf7aa1a9a5a |
| Source note | uspto-grants-2005_06 |