Methyl 4-(bromomethyl)benzoate → HCID 22392778, compound

HRID 1071387Notes

Reaction equation

HRID 1071387 reaction equation
Br[CH2:2][C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9]C)=[O:8])=[CH:5][CH:4]=1.[OH:13][C:14]1[CH:23]=[CH:22][CH:21]=[C:20]2[C:15]=1[CH:16]=[CH:17][CH:18]=[N:19]2>>[N:19]1[C:20]2[C:15](=[C:14]([O:13][CH2:2][C:3]3[CH:12]=[CH:11][C:6]([C:7]([OH:9])=[O:8])=[CH:5][CH:4]=3)[CH:23]=[CH:22][CH:21]=2)[CH:16]=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 256687Methyl 4-(bromomethyl)benzoateHCID 135441757Quinolin-5-ol

Product 1

HCID 22392778HCID 22392778, compound

Procedure

Methyl 4-(bromomethyl)benzoate was alkylated with commercially available 5-hydroxyquinoline using the analogous procedure as used for Example 202. MS found: (M+H)=280.

Sources & evidence

ORD record
ord-518cd95c1362426e99e86744c13c5434
Source dataset
uspto-grants-2005_06
Patent number
US06906053B2

Reaction notes

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