Water → 2-[[(4-Methyl-1H-benzimidazol-2-yl)sulfinyl]methyl]benzenamine hemihydrate

HRID 1071533Notes

Reaction equation

HRID 1071533 reaction equation
[CH3:1][C:2]1[C:10]2[N:9]=[C:8]([S:11][CH2:12][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[NH2:19])[NH:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.[OH2:20]>>[OH2:20].[CH3:1][C:2]1[C:10]2[N:9]=[C:8]([S:11]([CH2:12][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[NH2:19])=[O:20])[NH:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.[CH3:1][C:2]1[C:10]2[N:9]=[C:8]([S:11]([CH2:12][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[NH2:19])=[O:20])[NH:7][C:6]=2[CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 962WaterHCID 140646492-[[(4-Methyl-1H-benzimidazol-2-yl)thio]methyl]benzenamine

Product 1

HCID 697967602-[[(4-Methyl-1H-benzimidazol-2-yl)sulfinyl]methyl]benzenamine hemihydrate

Procedure

The title compound (740 mg) was prepared by the method of Example 3 using 900 mg of the title product of Example 7 instead of the title product of Example 2. Analysis. Calc'd. for C15H15N3OS*½ H2O: C, 61.20; H,5.48; N, 14.27; S, 10.89. Found: C, 61.21; H, 5.05; N, 13.88; S, 11.12.

Sources & evidence

ORD record
ord-cd3f44421b9d408cbbde720f809be002
Source dataset
uspto-grants-2005_06
Patent number
US06906078B2

Reaction notes

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