Water → HCID 178507579, compound

HRID 1071563Notes

Reaction equation

HRID 1071563 reaction equation
[OH:1][CH2:2][C:3]1[CH:20]=[CH:19][C:6]2[NH:7][C:8]([S:10][CH2:11][C:12]3[N:17]=[C:16]([NH2:18])[CH:15]=[CH:14][CH:13]=3)=[N:9][C:5]=2[CH:4]=1.[OH2:21]>>[OH:1][CH2:2][C:3]1[CH:20]=[CH:19][C:6]2[NH:7][C:8]([S:10]([CH2:11][C:12]3[N:17]=[C:16]([NH2:18])[CH:15]=[CH:14][CH:13]=3)=[O:21])=[N:9][C:5]=2[CH:4]=1

Participants

3

Reactant 2

HCID 962WaterHCID 178507578HCID 178507578, compound

Product 1

HCID 178507579HCID 178507579, compound

Procedure

The title compound was prepared by the method of Example 85 using 350 mg of 6-[[[5-(hydroxymethyl)-1H-benzimidazol-2-yl]thio]methyl]-2-pyridinamine (see Example 104) instead of 6-[(1H-benzimidazol-2-ylthio)methyl]-2-pyridinamine. Structure assignment was supported by the nmr and infrared spectra and by elemental analysis. Analysis. Calc'd. for C14H14N4SO2*¼ H2O: C, 54.80; H,4.60; N, 18.25; S, 10.44. Found: C, 54.85; H, 4.70; N, 18.01; S, 10.26.

Sources & evidence

ORD record
ord-7d55a0280ac44ad9ae841be219a84efd
Source dataset
uspto-grants-2005_06
Patent number
US06906078B2

Reaction notes

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