反应详情

温度

80 °C

A suspension of quinoxaline-6-carboxylic acid (1.8 g, 10.3 mmole) (Chem. Ber. 1953, 86, 1295) in SOCl2 (30 ml) was stirred at 80° C. for 3 h. The resulting yellow solution was concentrated by distillation, and the residue treated with toluene and concentrated to dryness in vacuo giving a pale beige solid (2.0 g, quant.). m/z [ESMS]: 203 [M+EtOH−Cl]+.

1. concentrationThe resulting yellow solution was concentrated by distillation
2. additionthe residue treated with toluene
3. concentrationconcentrated to dryness in vacuo
4. customgiving a pale beige solid (2.0 g, quant.)